Golden staph linked to SIDS deaths
Updated Thu Sep 11 16:38:00 EST 2008
Staph is one of the leading ones cause of sudden infant death.
Jeremy Brown: www.sxc.hu
It kills an average of 65 babies a year in Australia and its cause is still unknown.
Now research from Adelaide’s Women and Children’s Hospital has found that a possible cause of Sudden Infant Death Syndrome (SIDS) has been overlooked.
The study found that a strain of golden staph bacteria could be a trigger for the syndrome.
Associate Professor Paul Goldwater says he analysed the post mortem reports of more than 190 babies over a 25-year period to come to his conclusion.
"We believe that these pathogens are actually causing infection and they may be the cause of SIDS," he said.
"We found them in about a quarter of the cases of sudden infant death.
"Staph always is one of the leading ones and we found it in about 10 per cent."
Professor Goldwater says the golden staph infection he has analysed is the same type that most people are familiar with.
"What’s of particular note is that staph aureus, this golden staph, very commonly carries lethal toxins and as part of our research we found two-thirds of SIDS infants actually carry these lethal toxins in their intestines, as it happens," he said.
He says this could not only be a trigger for SIDS, but also be the cause which has been overlooked up until now.
Professor Goldwater has recommended that from now on post mortems look more carefully at whether this bacteria is present.
"Also in terms of the care of the baby, the sleeping surface is very important and babies should not be put down to sleep on sofas or in the parents’ bed because these are heavily contaminated sites, heavily contaminated with pathogenic bacteria," he said.
"And of course the recommendation is to put the baby down on their backs.
"We think the association with prone sleeping is that the baby is more likely to ingest or get colonised with these bacteria if their face is in contact with the sleeping surface."
However, one criticism of the study is that the cases were drawn over a long time span.
"Unfortunately or fortunately depending how you look at it, the comparison deaths are quite rare and so we have to look over a long period of time," Professor Goldwater said.
Despite this however, Professor Goldwater is extremely confident that this particular golden staph bacteria is a cause of SIDS and he also thinks other bacteria could be involved as well.
"There’s strong evidence that viruses probably play a role as a co-factor," he said.
"My PhD student Amanda Highet is doing genetic studies as well as the bacterial toxin studies and has had some very interesting findings with some genes that we believe make SIDS babies more susceptible to these bacterial toxins.
"And her preliminary data shows a very strong correlation with two particular gene mutations."
Professor Goldwater says this means that "almost certainly" there could also be a genetic factor involved in SIDS deaths.
"When you put all of these factors together that’s when the baby is at risk," he said.
Based on a report by Nance Haxton for The World Today
Posted Thu Sep 11 15:15:00 EST 2008
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